衰老与再生医学研究院


代表性论文:


 1.Yang F, Huang Y, Chen X, Liu L, Liao D, Zhang H, Huang G, Liu W, Zhu X, Wang W, Lobo CA, Yazdanbakhsh K, An X, Ju Z.  Deletion of a flippase subunit Tmem30a in hematopoietic cells impairs mouse fetal liver erythropoiesis. Haematologica. 2019 Feb 28;pii: haematol.2018.203992. (影响因子9.09).


 2.Wang X, Gao Y, Gao J, Li M, Zhou M, Wang J, Pang Y, Cheng H, Yuan C, Chu Y, Jiang Y, Zhou J, Luo HR, Ju Z, Cheng T, Yuan W. Rheb1 loss leads to increased hematopoietic stem cell proliferation and myeloid-biased differentiation in vivo. Haematologica. 2019 Feb;104(2):245-255. (影响因子9.09).


 3.Wang HZuo HLiu JWen FGao YZhu XLiu BXiao FWang WHuang GShen BJu Z. Loss of YTHDF2 mediated m6A-dependent mRNA clearance facilitates hematopoietic stem cell regeneration. Cell Res. 2018 Oct;28(10):1035-1038.(影响因子15.393).


 4.Diao DWang HLi TShi ZJin XSperka TZhu XZhang MYang FCong YShen LZhan QYan JSong ZJu Z. Telomeric epigenetic response mediated by Gadd45a regulates stem cell aging and lifespan. EMBO Rep. 2018 Oct;19(10). pii: e45494. (影响因子8.749)


 5.Tang H, Wang H, Cheng X, Fan X, Yang F, Zhang M,Chen Y, Tian Y, Liu C, Shao D,  Jiang B, Dou Y, Cong Y, Xing J, Zhang X, Yi X, Songyang Z,Ma W,Zhao Y,Wang X, Ma J,  Myriam Gorospe, Ju Z , Wang W. HuR regulates telomerase activity through TERC methylation. Nature communication.2018 Jun 7;9(1):2213. (影响因子12.353)


 6.Kang YZhang HZhao YWang YWang WHe YZhang WZhang WZhu XZhou YZhang LJu ZShi L. Telomere Dysfunction Disturbs Macrophage Mitochondrial Metabolism and the NLRP3 Inflammasome through the PGC-1α/TNFAIP3 Axis. Cell Rep. 2018 Mar 27;22(13):3493-3506. (影响因子8.032)


 7.Zhang C, Yi W, Li F, Du X, Wang H, Wu P, Peng C, Luo M, Hua W, Wong CC, Lee JJ, Li W, Chen Z, Ying S, Ju Z, Shen H. Eosinophil-derived CCL-6 impairs hematopoietic stem cell homeostasis. Cell Res. 2018 Mar; 28(3):323-335.(影响因子15.393)


 8.Liu J,Wang Y,Song L,Zeng L,Yi W,Liu T,Chen H,Wang M,Ju Z,Cong Y. A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1a stability. Nature Communications. 2017 Jan 27;8:14186. (影响因子12.353)